- Industry: Government
- Number of terms: 33950
- Number of blossaries: 0
- Company Profile:
United States Department of Health and Human Services, Radiation Emergency Medical Management
A substance being studied in the treatment of some types of cancer. M5A is a monoclonal antibody that binds to a protein called CEA on the surface of some tumor cells. It is linked to a radioisotope called yttrium Y 90, which may help kill the cancer cells. Yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A is a type of radioimmunoconjugate and a type of radiopharmaceutical.
Industry:Health care
A substance being studied in the treatment of liver cancer. HuAFP31 is a monoclonal antibody that can bind to tumor cells that make a protein called alpha fetoprotein (AFP). It is linked to a radioactive substance called yttrium Y 90, which may help kill the cancer cells. Yttrium Y 90 DOTA monoclonal antibody HuAFP31 is a type of radioimmunoconjugate.
Industry:Health care
A substance being studied in the treatment of advanced pancreatic cancer. HuPAM4 is a monoclonal antibody that can locate and bind to pancreatic cancer cells. It is linked to a radioactive substance called yttrium Y90, which may help kill cancer cells. Yttrium Y 90 DOTA monoclonal antibody HuPAM4 is a type of radioimmunoconjugate.
Industry:Health care
A compound that contains the radioisotope yttrium Y 90 linked to the chemical biotin. Biotin is a molecule that binds strongly to the chemical streptavidin. Yttrium Y 90 DOTA-biotin will find tumor cells in the body that have been targeted by an antibody linked to streptavidin and kill them. It is being studied together with CC49-streptavidin in the treatment of cancer. Also called 90Y-DOTA-biotin.
Industry:Health care
A substance being studied in the treatment of some types of cancer. Yttrium Y 90 DOTA-tyr3-octreotide contains yttrium Y 90 (a radioactive form of the metal yttrium) attached to a molecule that binds to certain types of neuroendocrine tumors (tumors that come from cells that release hormones). The radioactivity from yttrium Y 90 may kill the cancer cells. Also called yttrium Y 90 edotreotide and yttrium Y 90 SMT 487.
Industry:Health care
A substance being studied in the treatment of some types of cancer. Yttrium Y 90 edotreotide contains yttrium Y 90 (a radioactive form of the metal yttrium) attached to a molecule that binds to certain types of neuroendocrine tumors (tumors that come from cells that release hormones). The radioactivity from yttrium Y 90 may kill the cancer cells. Also called yttrium Y 90 DOTA-tyr3-octreotide and yttrium Y 90 SMT 487.
Industry:Health care
A radiolabeled monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment of other types of B-cell tumors. It is made up of the monoclonal antibody ibritumomab plus the radioisotope yttrium Y 90. It binds to the protein called CD20, which is found on B cells. The radiation in the yttrium Y 90 may kill the cancer cells. Yttrium Y 90 ibritumomab tiuxetan is a type of radiopharmaceutical. Also called IDEC-Y2B8, Y 90 ibritumomab tiuxetan, and Y 90 Zevalin.
Industry:Health care
A substance being studied in the treatment of some types of cancer. Yttrium Y 90 SMT 487 contains yttrium Y 90 (a radioactive form of the metal yttrium) attached to a molecule that binds to certain types of neuroendocrine tumors (tumors that come from cells that release hormones). The radioactivity from yttrium Y 90 may kill the cancer cells. Also called yttrium Y 90 DOTA-tyr3-octreotide and yttrium Y 90 edotreotide.
Industry:Health care
Stage III anal cancer is divided into stages IIIA and IIIB. In stage IIIB, the tumor may be any size and has spread to (1) nearby organs and to lymph nodes near the rectum; or (2) lymph nodes on one side of the pelvis and/or groin, and may have spread to nearby organs; or (3) lymph nodes near the rectum and in the groin, and/or to lymph nodes on both sides of the pelvis and/or groin, and may have spread to nearby organs.
Industry:Health care
Stage III breast cancer is divided into stages IIIA, IIIB, and IIIC. In stage IIIB, the tumor may be any size and cancer (1) has spread to the chest wall and/or the skin of the breast; and (2) may have spread to axillary (under the arm) lymph nodes that may be attached to each other or to other structures, or the cancer may have spread to lymph nodes near the breastbone.
Industry:Health care
