- Industry: Government
- Number of terms: 33950
- Number of blossaries: 0
- Company Profile:
United States Department of Health and Human Services, Radiation Emergency Medical Management
A substance being studied in the treatment of breast cancers caused by mutations (changes) in the BRCA1 and BRCA2 genes. It is also being studied in the treatment of other types of cancer. It blocks an enzyme involved in many functions of the cell, including the repair of DNA damage. DNA damage may be caused by normal cell actions, UV light, some anticancer drugs, and radiation used to treat cancer. BSI-201 may cause cancer cells to die. It is a type of poly(ADP-ribose) polymerase inhibitor. Also called iniparib and PARP-1 inhibitor BSI-201.
Industry:Health care
A chimeric (made from human and mouse proteins) monoclonal antibody being studied in the treatment of advanced kidney cancer and other types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. cCLB8 works by blocking inflammation and tumor growth. Also called anti-IL-6 chimeric monoclonal antibody and CNTO 328.
Industry:Health care
The most common type of Hodgkin lymphoma, which is a cancer of the immune system. Classical Hodgkin lymphoma is marked by the presence of a type of cell called the Reed-Sternberg cell.
Industry:Health care
A substance being studied in PET imaging to detect certain types of tumors. Copper Cu 64 is a radioactive substance. It is linked to ATSM, which is taken up by tissues that have low levels of oxygen, such as some tumor tissues. A PET scanner is used to detect which cells in the body have taken up copper Cu 64-ATSM. It is a type of radioimaging agent.
Industry:Health care
A protein involved in normal cell growth. It is found on some types of cancer cells, including breast and ovarian. Cancer cells removed from the body may be tested for the presence of c-erbB-2 to help decide the best type of treatment. c-erbB-2 is a type of receptor tyrosine kinase. Also called HER2/neu, human EGF receptor 2, and human epidermal growth factor receptor 2.
Industry:Health care
A protein that is made by many different types of cells and is involved in processes that take place both inside and outside of the cell. It is made in larger amounts in inflammatory diseases such as rheumatoid arthritis, and in some types of cancer. It is being studied as a biomarker for breast cancer. Also called S100 calcium binding protein A8.
Industry:Health care
A protein that is made by many different types of cells and is involved in processes that take place both inside and outside of the cell. It is made in larger amounts in inflammatory diseases such as rheumatoid arthritis, and in some types of cancer. It is being studied as a biomarker for breast cancer. Also called S100 calcium binding protein A9.
Industry:Health care
A procedure in which a small amount of carbon-11 choline (a radioactive form of the vitamin choline) is injected into a vein. A scanner and a computer are used to make detailed pictures of areas inside the body where the carbon-11 choline collects. Cancer cells take up more carbon-11 choline than normal cells, so the pictures can be used to find cancer cells in the body. Also called C-11 choline PET-CT scan.
Industry:Health care
A chemotherapy combination used to treat endometrial, ovarian, head and neck cancers, and non-small cell lung cancer that has spread. It includes the drugs carboplatin and paclitaxel (Taxol). Also called Carbo-Tax regimen, CaT regimen, and PC regimen.
Industry:Health care
A chemotherapy combination used to treat advanced, nonsquamous non-small cell lung cancer. It includes the drugs carboplatin, paclitaxel (Taxol), and bevacizumab. Also called carboplatin-paclitaxel-bevacizumab regimen.
Industry:Health care
